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ICD-10-CM Codes D50-D89 D80-D89

Section D80-D89 Certain disorders involving the immune mechanism D80-D89

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( D78 )

Includes for D80-D89:

defects in the complement system
immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
sarcoidosis

Excludes-1 for D80-D89:

autoimmune disease (systemic) NOS (M35.9)
functional disorders of polymorphonuclear neutrophils (D71)
human immunodeficiency virus [HIV] disease (B20)

Code List:

D80

Code hierarchy

D80 Immunodeficiency with predominantly antibody defects
- D80.0 Hereditary hypogammaglobulinemia
- D80.1 Nonfamilial hypogammaglobulinemia
- D80.2 Selective deficiency of immunoglobulin A [IgA]
- D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4 Selective deficiency of immunoglobulin M [IgM]
- D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7 Transient hypogammaglobulinemia of infancy
- D80.8 Other immunodeficiencies with predominantly antibody defects
- D80.9 Immunodeficiency with predominantly antibody defects, unspecified

Immunodeficiency with predominantly antibody defects

D81

Code hierarchy

D81 Combined immunodeficiencies
- D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.3 Adenosine deaminase [ADA] deficiency
  - D81.30 Adenosine deaminase deficiency, unspecified
  - D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
  - D81.32 Adenosine deaminase 2 deficiency
  - D81.39 Other adenosine deaminase deficiency
- D81.4 Nezelof's syndrome
- D81.5 Purine nucleoside phosphorylase [PNP] deficiency
- D81.6 Major histocompatibility complex class I deficiency
- D81.7 Major histocompatibility complex class II deficiency
- D81.8 Other combined immunodeficiencies
  - D81.81 Biotin-dependent carboxylase deficiency
    - D81.810 Biotinidase deficiency
    - D81.818 Other biotin-dependent carboxylase deficiency
    - D81.819 Biotin-dependent carboxylase deficiency, unspecified
  - D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
  - D81.89 Other combined immunodeficiencies
- D81.9 Combined immunodeficiency, unspecified

Combined immunodeficiencies

D82

Code hierarchy

D82 Immunodeficiency associated with other major defects
- D82.0 Wiskott-Aldrich syndrome
- D82.1 Di George's syndrome
- D82.2 Immunodeficiency with short-limbed stature
- D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
- D82.4 Hyperimmunoglobulin E [IgE] syndrome
- D82.8 Immunodeficiency associated with other specified major defects
- D82.9 Immunodeficiency associated with major defect, unspecified

Immunodeficiency associated with other major defects

D83

Code hierarchy

D83 Common variable immunodeficiency
- D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
- D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
- D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
- D83.8 Other common variable immunodeficiencies
- D83.9 Common variable immunodeficiency, unspecified

Common variable immunodeficiency

D84

Code hierarchy

D84 Other immunodeficiencies
- D84.0 Lymphocyte function antigen-1 [LFA-1] defect
- D84.1 Defects in the complement system
- D84.8 Other specified immunodeficiencies
  - D84.81 Immunodeficiency due to conditions classified elsewhere
  - D84.82 Immunodeficiency due to drugs and external causes
    - D84.821 Immunodeficiency due to drugs
    - D84.822 Immunodeficiency due to external causes
  - D84.89 Other immunodeficiencies
- D84.9 Immunodeficiency, unspecified

Other immunodeficiencies

D86

Code hierarchy

D86 Sarcoidosis
- D86.0 Sarcoidosis of lung
- D86.1 Sarcoidosis of lymph nodes
- D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
- D86.3 Sarcoidosis of skin
- D86.8 Sarcoidosis of other sites
  - D86.81 Sarcoid meningitis
  - D86.82 Multiple cranial nerve palsies in sarcoidosis
  - D86.83 Sarcoid iridocyclitis
  - D86.84 Sarcoid pyelonephritis
  - D86.85 Sarcoid myocarditis
  - D86.86 Sarcoid arthropathy
  - D86.87 Sarcoid myositis
  - D86.89 Sarcoidosis of other sites
- D86.9 Sarcoidosis, unspecified

Sarcoidosis

D89

Code hierarchy

D89 Other disorders involving the immune mechanism, not elsewhere classified
- D89.0 Polyclonal hypergammaglobulinemia
- D89.1 Cryoglobulinemia
- D89.2 Hypergammaglobulinemia, unspecified
- D89.3 Immune reconstitution syndrome
- D89.4 Mast cell activation syndrome and related disorders
  - D89.40 Mast cell activation, unspecified
  - D89.41 Monoclonal mast cell activation syndrome
  - D89.42 Idiopathic mast cell activation syndrome
  - D89.43 Secondary mast cell activation
  - D89.44 Hereditary alpha tryptasemia
  - D89.49 Other mast cell activation disorder
- D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
  - D89.81 Graft-versus-host disease
    - D89.810 Acute graft-versus-host disease
    - D89.811 Chronic graft-versus-host disease
    - D89.812 Acute on chronic graft-versus-host disease
    - D89.813 Graft-versus-host disease, unspecified
  - D89.82 Autoimmune lymphoproliferative syndrome [ALPS]
  - D89.83 Cytokine release syndrome
    - D89.831 Cytokine release syndrome, grade 1
    - D89.832 Cytokine release syndrome, grade 2
    - D89.833 Cytokine release syndrome, grade 3
    - D89.834 Cytokine release syndrome, grade 4
    - D89.835 Cytokine release syndrome, grade 5
    - D89.839 Cytokine release syndrome, grade unspecified
  - D89.84 IgG4-related disease
  - D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified
- D89.9 Disorder involving the immune mechanism, unspecified

Other disorders involving the immune mechanism, not elsewhere classified