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ICD-10-CM Codes K00-K95 K70-K77 K74 K74.3
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2025 Primary Biliary Cirrhosis ICD 10 Code K74.3

Effective Date: 10/01/2015 To 09/30/2025

Primary biliary cirrhosis

CMS-HCC-V24 CMS-HCC-V28 RxHCC Age Gender Maternity Acute or Chronic MCC
28 68 59 -- -- -- Chronic No
Applicable To for K74.3:

  • Chronic nonsuppurative destructive cholangitis

  • Primary biliary cholangitis

Excludes-2 for K74.3:

  • primary sclerosing cholangitis (K83.01)

Back-references to K74.3
  • Charcot's
    • cirrhosis K74.3
    • Cholangitis(ascending) (recurrent) (secondary) (stenosing) (suppurative) K83.09
      • chronic nonsuppurative destructive K74.3
      • Cirrhosis, cirrhotic(hepatic) (liver) K74.60
        • Charcot's K74.3
          • Hanot's(hypertrophic) K74.3
            • Todd's K74.3
              • biliary(cholangiolitic) (cholangitic) (hypertrophic) (obstructive) (pericholangiolitic) K74.5
                • primary K74.3
                • cholangiolitic, cholangitic, cholostatic(primary) K74.3
                  • hypertrophic K74.3
                    • monolobular K74.3
                      • unilobar K74.3
                      • Hanot's cirrhosis or disease K74.3
                      • Todd's
                        • cirrhosis K74.3
                          • Related Medications for K74.3

                          • colchicine, penicillamine, ursodeoxycholate, obeticholic acid

                          Chapter, Section and Diagnosis Prefix for K74.3
                            K00-K95 :

                            Diseases of the digestive system

                            K70-K77 :

                            Diseases of liver

                            K74 :

                            Fibrosis and cirrhosis of liver

                          What is Primary Biliary Cirrhosis ICD 10?

                          Cholangitis refers to inflammation in the bile ducts. Biliary means related to the bile ducts, and primary indicates that the disease itself is the original cause of inflammation in the bile ducts, not due to another condition like an infection or blockage. Primary biliary cholangitis is a disorder characterized by inflammation and gradual destruction of the bile ducts.

                          Causes of Primary Biliary Cholangitis 10 (K74.3):

                          The exact cause of the primary biliary cholangitis is unclear. Many experts believe it is an autoimmune disease, where the body attacks its own cells.

                          Symptoms for Primary Biliary Cirrhosis ICD 10 (K74.3):

                          • Fatigue
                          • Itchy skin
                          • Dry eyes and mouth
                          • Jaundice (yellowing of the skin and eyes)
                          • Pain in the upper right abdomen
                          • Enlarged spleen (splenomegaly)
                          • Swollen feet and ankles
                          • Weight loss

                          Diagnostics of Primary Biliary Cirrhosis ICD 10:

                          • Blood tests:

                            Liver function tests, antibody tests for autoimmune disease, and cholesterol test.

                          • Imaging tests:

                            Ultrasound, FibroScan, MRCP, and MRE to detect liver scarring and bile duct abnormalities.

                          Treatment for Primary Biliary Cirrhosis ICD 10:

                          There's no cure for it, but medications can slow down the progression of the disease. These include:

                          • Ursodeoxycholic acid - ursodiol (Actigall, Urso)
                          • Obeticholic acid (Ocaliva)
                          • Fibrates (Tricor)
                          • Budesonide

                          Surgery:

                          When medications no longer manage primary biliary cholangitis and the liver fails, a liver transplant may be necessary to prolong life.